Important caveat, especially when lupus arthritis is concerned, but also with respect to any other clinical criterion. Derivation and validation of systemic lupus international. Derivation and validation of the systemic lupus international collaborating clinics. Slicc criteria for sle slicc classification criteria for. Derivation and validation of the systemic lupus international collaborating clinics classi. Slicc classification criteria for sle amith balachandran, department of anaesthesia, cmc vellore, and ashish jacob mathew, assistant professor, department of rheumatology, cmc, vellore. A detailed comparison of the classification criteria from 1971, 1982, 1997 and 2012 is depicted in the table below.
The 2012 revised slicc criteria for classification of. Background systemic lupus erythematosus sle is a disease with an autoimmune origin, which occurs nine times more often. Figure 1 natural history of systemic lupus erythematosus. To ensure that there is a consistent definition of sle for the purposes of research and surveillance, classification criteria for sle are needed. Reprinted with permission from bertsias gk, salmon je, boumpas dt. Derivation and validation of systemic lupus international collaborating clinics classification criteria for systemic lupus erythematosus.
The systemic lupus international collaborating clinics slicc group revised and validated the american college of rheumatology acr systemic lupus erythematosus sle classification criteria in order to improve clinical relevance, meet stringent methodology requirements, and incorporate new knowledge regarding the immunology of sle. Derivation and validation of the systemic lupus international collaborating clinics classification criteria for systemic lupus erythematosus. American college of rheumatology guidelines for screening, treatment, and management of lupus nephritis bevra h. Systemic lupus erythematosus sle is a prototypic autoimmune disease, affecting more than 300,000 in the united states and millions worldwide. Slicc, systemic lupus international collaborating clinicsamerican college of rheumatology damage index. General features, immunopathogeny and relevant antigens abstract. To develop recommendations for the diagnosis, management and treatment of lupus nephritis in brazil. Lupus eritematoso generalizado, autoanticuerpos, inmunopatogenia.
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